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A base is an organic nitrogenous molecule which, when covalently bonded to a pentose sugar, which is in turn linked to phosphate molecules, forms a nucleotide. There are four types of bases in DNA: adenine, thymine, guanine and cytosine. Generally, purine bases such as adenine and guanine form hydrogen bonds with pyrimidine bases such as thymine and cytosine. According to Watson-Crick principles in DNA, adenine only base pairs with thymine and cytosine only base pairs with guanine. Strong hydrogen bonds form between complementary bases. These hydrogen bonds are broken during semi-conservative replication so the DNA molecule can unwind. | A base is an organic nitrogenous molecule which, when covalently bonded to a pentose sugar, which is in turn linked to phosphate molecules, forms a <ref>nucleotide</ref>. There are four types of bases in DNA: adenine, thymine, guanine and cytosine. Generally, purine bases such as adenine and guanine form hydrogen bonds with pyrimidine bases such as thymine and cytosine. According to Watson-Crick principles in DNA, adenine only base pairs with thymine and cytosine only base pairs with guanine. Strong hydrogen bonds form between complementary bases. These hydrogen bonds are broken during semi-conservative replication so the DNA molecule can unwind. |
Revision as of 15:29, 8 December 2010
A base is an organic nitrogenous molecule which, when covalently bonded to a pentose sugar, which is in turn linked to phosphate molecules, forms a [1]. There are four types of bases in DNA: adenine, thymine, guanine and cytosine. Generally, purine bases such as adenine and guanine form hydrogen bonds with pyrimidine bases such as thymine and cytosine. According to Watson-Crick principles in DNA, adenine only base pairs with thymine and cytosine only base pairs with guanine. Strong hydrogen bonds form between complementary bases. These hydrogen bonds are broken during semi-conservative replication so the DNA molecule can unwind.
- ↑ nucleotide