TRNA: Difference between revisions
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<u>'''Transter RNA (tRNA)'''</u> | <u>'''Transter RNA (tRNA)'''</u> | ||
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Transfer RNA molecules (tRNA's) are small RNA molecules usually approximately 80 [[Nucleotide|nucleotides]] in length, that function as adaptor molecules during the [[Translation|translation]] of mRNA into an [[Amino acid|amino acid sequence]]<ref name="null">Snustad, D. Peter. (2010). Principles Of Genetics.Hobeken: Wiley &amp;amp;amp;amp;amp;amp;amp;amp; Sons</ref>. | Transfer RNA molecules (tRNA's) are small RNA molecules usually approximately 80 [[Nucleotide|nucleotides]] in length, that function as adaptor molecules during the [[Translation|translation]] of mRNA into an [[Amino acid|amino acid sequence]]<ref name="null">Snustad, D. Peter. (2010). Principles Of Genetics.Hobeken: Wiley &amp;amp;amp;amp;amp;amp;amp;amp;amp; Sons</ref>. | ||
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The structure of tRNA arises through the ability of RNA to fold into three-dimensional shapes using [[Watson and Crick|Watson and Crick ]] | The structure of tRNA arises through the ability of RNA to fold into three-dimensional shapes using [[Watson and Crick|Watson and Crick base]] pairing. If there are large enough regions of overlap tRNA will fold into a shape that resembles a cloverleaf. This will undergo further folding, by [[Hydrogen bonds|hydrogen bonding]], to form a compact L-shaped structure.<ref name="null">Alberts, Bruce et al.(2009). New York: Garland Science</ref> | ||
The cloverleaf structure of tRNA is composed of an anticodon, a triplet of nucleotides that is complementary to corresponding [[Codon|codons]] on mRNA nolecules. tRNAS also have a short single stranded region at a tRNAs 3' end where amino acids that match an [[MRNA|mRNA]] codon are attached<ref>Champe et al.(2008). Biochemistry. Baltimore: Lippincott Williams &amp; Wilkins</ref>. | The cloverleaf structure of tRNA is composed of an anticodon, a triplet of nucleotides that is complementary to corresponding [[Codon|codons]] on mRNA nolecules. tRNAS also have a short single stranded region at a tRNAs 3' end where amino acids that match an [[MRNA|mRNA]] codon are attached<ref>Champe et al.(2008). Biochemistry. Baltimore: Lippincott Williams &amp;amp; Wilkins</ref>. | ||
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<u>'''Function'''</u> | |||
The amino acids that bond to produce a protein do not bind to mRNA. They require an adaptor molecule to bind to mRNA at one point and to the amino acid at another. This adaptor molecule is tRNA. | The amino acids that bond to produce a protein do not bind to mRNA. They require an adaptor molecule to bind to mRNA at one point and to the amino acid at another. This adaptor molecule is tRNA. | ||
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<u>'''References'''</u> | <u>'''References'''</u> | ||
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<references /> | <references /> | ||
Revision as of 20:20, 15 December 2010
Transter RNA (tRNA)
Transfer RNA molecules (tRNA's) are small RNA molecules usually approximately 80 nucleotides in length, that function as adaptor molecules during the translation of mRNA into an amino acid sequence[1].
Structure
The structure of tRNA arises through the ability of RNA to fold into three-dimensional shapes using Watson and Crick base pairing. If there are large enough regions of overlap tRNA will fold into a shape that resembles a cloverleaf. This will undergo further folding, by hydrogen bonding, to form a compact L-shaped structure.[1]
The cloverleaf structure of tRNA is composed of an anticodon, a triplet of nucleotides that is complementary to corresponding codons on mRNA nolecules. tRNAS also have a short single stranded region at a tRNAs 3' end where amino acids that match an mRNA codon are attached[2].
Function
The amino acids that bond to produce a protein do not bind to mRNA. They require an adaptor molecule to bind to mRNA at one point and to the amino acid at another. This adaptor molecule is tRNA.
<u
References