Clonal selection: Difference between revisions
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Clonal selection gives rise to a diverse of unique [[antigen receptor|antigen receptors]]. However, self-recognising receptors are made as well. If native antigens i.e. on a tissue surface is recognised, [[antigen|antigen]] could bind and attack native [[organs|organs]]. That's why [[Clonal Deletion|Clonal Deletion]] is important as during the development of [[lymphocytes|lymphocytes]], these self-reacting antigen receptors are removed before they can mature<ref>(1) K. Murphy, C. Weaver. Janeway's Immunobiology; 9th Edition; Garland Science, Taylor &amp;amp; Francis Group, LLC; 15-16p.</ref>. | |||
==== References | ==== References ==== | ||
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Revision as of 17:03, 23 October 2018
Clonal selection gives rise to a diverse of unique antigen receptors. However, self-recognising receptors are made as well. If native antigens i.e. on a tissue surface is recognised, antigen could bind and attack native organs. That's why Clonal Deletion is important as during the development of lymphocytes, these self-reacting antigen receptors are removed before they can mature[1].
References
- ↑ (1) K. Murphy, C. Weaver. Janeway's Immunobiology; 9th Edition; Garland Science, Taylor &amp; Francis Group, LLC; 15-16p.