Pleckstrin homology: Difference between revisions
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A pleckstrin homology [[Protein_domain|domain]] is the 11th most comain domain in the [[human|human]] [[proteome|proteome]]. At around 100 [[amino acids|amino acids]] long the domain has a high affinity and high specificity for [[phosphoinositides|phosphoinositides]] with about 10% of domains sharing this property. The exact function is unknown but they are thought to be components in the cells [[cytoskeleton|cytoskeleton]] or involved in [[intracellular signalling|intracellular signalling]]<ref>https://www.ncbi.nlm.nih.gov/pubmed/17233582</ref>. <br> | |||
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Latest revision as of 05:57, 24 October 2018
A pleckstrin homology domain is the 11th most comain domain in the human proteome. At around 100 amino acids long the domain has a high affinity and high specificity for phosphoinositides with about 10% of domains sharing this property. The exact function is unknown but they are thought to be components in the cells cytoskeleton or involved in intracellular signalling[1].