NAD+: Difference between revisions

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NAD stands for [[Nicotinamide|nicotinamide]] [[Adenine|adenine]] dinucluotide. NAD<sup>+</sup> is the oxidised form, and [[NADH|NADH]] is the reduced form, which exist in an equilibrium, with NAD<sup>+</sup> being favoured. Oxidation of fuel molecules produces one hydrogen ion and two&nbsp;[[Electrons|electrons]]<ref>Berg J.M., Stryer L., Tymoczko J.L. (2012) Biochemistry, 7th Edition, New York: W.H. Freeman and Company. p454</ref> which are used to reduce NAD<sup>+</sup> in the reaction of [[Ethanol|ethanol]] + [[Dehydrogenase|dehydrogenase]] to form [[Ethanal|ethanal]] + NADH + H<sup>+</sup>. Also NADH<sup>+</sup> is oxidised to NAD in [[Oxidative phosphorylation|oxidative phosphoryation]] which is directly linked to [[ATP|ATP]] synthesis&nbsp;<ref>Alberts et al., 2008, Molecular Biology of the Cell,5th ed.,New York, Garland Science, Taylor and Francis Group p.86</ref>.  
NAD stands for [[Nicotinamide|nicotinamide]] [[Adenine|adenine]] dinucluotide. NAD<sup>+</sup> is the oxidised form, and [[NADH|NADH]] is the reduced form, which exist in an equilibrium, with NAD<sup>+</sup> being favoured. Oxidation of fuel molecules produces one hydrogen ion and two&nbsp;[[Electrons|electrons]]<ref>Berg J.M., Stryer L., Tymoczko J.L. (2012) Biochemistry, 7th Edition, New York: W.H. Freeman and Company. p454</ref> which are used to reduce NAD<sup>+</sup> in the reaction of [[Ethanol|ethanol]] + [[Dehydrogenase|dehydrogenase]] to form [[Ethanal|ethanal]] + NADH + H<sup>+</sup>. Also NADH<sup>+</sup> is oxidised to NAD in [[Oxidative phosphorylation|oxidative phosphoryation]] which is directly linked to [[ATP|ATP]] synthesis<ref>Alberts et al., 2008, Molecular Biology of the Cell,5th ed.,New York, Garland Science, Taylor and Francis Group p.86</ref>.  


=== References  ===
=== References  ===


<references />
<references />

Latest revision as of 20:50, 6 December 2018

NAD stands for nicotinamide adenine dinucluotide. NAD+ is the oxidised form, and NADH is the reduced form, which exist in an equilibrium, with NAD+ being favoured. Oxidation of fuel molecules produces one hydrogen ion and two electrons[1] which are used to reduce NAD+ in the reaction of ethanol + dehydrogenase to form ethanal + NADH + H+. Also NADH+ is oxidised to NAD in oxidative phosphoryation which is directly linked to ATP synthesis[2].

References

  1. Berg J.M., Stryer L., Tymoczko J.L. (2012) Biochemistry, 7th Edition, New York: W.H. Freeman and Company. p454
  2. Alberts et al., 2008, Molecular Biology of the Cell,5th ed.,New York, Garland Science, Taylor and Francis Group p.86