Isoleucine: Difference between revisions
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Isoleucine is a [[Hydrophobic|hydrophobic]] neutral [[Amino acids|amino acid]], the reason why it is [[Hydrophobic|hydrophobic]] is because it has an [[Aliphatic|aliphatic]] side chain. Due to this hydrophobic characteristic of the amino acid, it interacts more favourably with other [[Aliphatic|aliphatic]] [[Amino acid residues|residues]], such as: alanine, valine and leucine, and other [[Non-polar amino acids|non-polar amino acids]]. This is one of the main | Isoleucine is a [[Hydrophobic|hydrophobic]] neutral [[Amino acids|amino acid]], the reason why it is [[Hydrophobic|hydrophobic]] is because it has an [[Aliphatic|aliphatic]] side chain. Due to this hydrophobic characteristic of the amino acid, it interacts more favourably with other [[Aliphatic|aliphatic]] [[Amino acid residues|residues]], such as: alanine, valine and leucine, and other [[Non-polar amino acids|non-polar amino acids]]. This is one of the main factors in stabilizing the folded conformations of proteins.<ref>Proteins structures and molecular properties, second edition, Thomas E. Creighton... pg 7</ref> Isoleucine has an additional [[Chiral centre|chiral centre]] at [[Carbon|carbon]] 3 <ref>Berg J., Tymoczko J and Stryer L. (2007) Biochemistry, 6th edition, New York: WH Freeman</ref><ref>Berg, J. M., Tymoczko, J. L., &amp;amp;amp;amp; Stryer, L. (2002). Biochemistry (5th ed.). New York: W.H. Freeman.</ref>. <br> | ||
[[Image:Isoleucine.png]] | [[Image:Isoleucine.png]] | ||
Revision as of 20:19, 9 December 2018
Isoleucine is a hydrophobic neutral amino acid, the reason why it is hydrophobic is because it has an aliphatic side chain. Due to this hydrophobic characteristic of the amino acid, it interacts more favourably with other aliphatic residues, such as: alanine, valine and leucine, and other non-polar amino acids. This is one of the main factors in stabilizing the folded conformations of proteins.[1] Isoleucine has an additional chiral centre at carbon 3 [2][3].
