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'''Guanosine diphosphate (GDP)''' | '''Guanosine diphosphate (GDP)''' | ||
Molecular formula: C<sub>10</sub>H<sub>15</sub>N<sub>5</sub>O<sub>11</sub>P<sub>2</sub><ref>http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=8977#x304</ref> | |||
Guanosine diphosphate is a [[Purine|purine]] [[Nucleoside|nucleoside]] diphosphate, and is a product of the [[Dephosphorylation|dephosphorylation]] of guanosine triphosphate ([[GTP|GTP]]) by [[GTPase|GTPases]]. The conversion of GTP to GDP (and vice versa) has a physiological involvment in [[G-proteins|G-Protein]] signal transduction, whereby the G-Protein exchanges it's bound GDP for GTP, leaving it in an active state. For the conversion GDP to [[GTP|GTP]], the enzymes [[Pyruvate kinase|pyruvate kinase]] and [[Phosphoenolpyruvate|phosphoenolpyruvate]] are necessary.<ref>http://www.uscnk.com/directory/Guanosine-6883.htm</ref><br> | |||
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Revision as of 15:14, 1 November 2011
Guanosine diphosphate (GDP)
Molecular formula: C10H15N5O11P2[1]
Guanosine diphosphate is a purine nucleoside diphosphate, and is a product of the dephosphorylation of guanosine triphosphate (GTP) by GTPases. The conversion of GTP to GDP (and vice versa) has a physiological involvment in G-Protein signal transduction, whereby the G-Protein exchanges it's bound GDP for GTP, leaving it in an active state. For the conversion GDP to GTP, the enzymes pyruvate kinase and phosphoenolpyruvate are necessary.[2]