GTPase: Difference between revisions
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== <u>'''Overview'''</u> == | == <u>'''Overview'''</u> == | ||
GTPases are a group of [[Enzyme|enzymes]] which hydrolyse [[GTP|GTP]] to [[GDP|GDP]] (a [[Phosphate|phosphate]] group is removed). They play an important roll in [[ | GTPases are a group of [[Enzyme|enzymes]] which hydrolyse [[GTP|GTP]] to [[GDP|GDP]] (a [[Phosphate|phosphate]] group is removed). They play an important roll in [[Cell signalling|cell signalling]] pathways for example, GTP/GDP bound [[G-proteins|G proteins]] have intrinsic GTPase activity to slowly reset themselves to their resting state state once it has fullfilled its function<ref>Berg J, Tymoczko J and Stryer L, 2007. Biochemistry, 6th Edition, New York: W.H.Freeman &amp; Co Ltd. (page 387)</ref>. They are also involved in the synthesis of [[Proteins|proteins]] at the [[Ribosomes|Ribosome]].<ref>Berg J, Tymoczko J and Stryer L, 2007. Biochemistry, 6th Edition, New York: W.H.Freeman & Co Ltd. (page 881)</ref> | ||
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Revision as of 15:47, 13 November 2011
Overview
GTPases are a group of enzymes which hydrolyse GTP to GDP (a phosphate group is removed). They play an important roll in cell signalling pathways for example, GTP/GDP bound G proteins have intrinsic GTPase activity to slowly reset themselves to their resting state state once it has fullfilled its function[1]. They are also involved in the synthesis of proteins at the Ribosome.[2]