Intermediate filaments: Difference between revisions
mNo edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
Intermediate filaments are a component of [[Cytoskeleton|cytoskeleton]]. They are around 10 nm, and are present in both [[Cytoplasm|cytoplasm]] and [[Nucleus|nucleus]]. These help provide the cell with mechanical strength and are also strong and stable. The different types of intermediate filaments that can be found in the [[Cytoplasm|cytoplasm]] of different cells can be used in tumour characterisation techniques within the health and research industries. Different categories of cytoplasmic intermediate filaments are found in; the [[ | Intermediate filaments are a component of [[Cytoskeleton|cytoskeleton]]. They are around 10 nm, and are present in both [[Cytoplasm|cytoplasm]] and [[Nucleus|nucleus]]. These help provide the cell with mechanical strength and are also strong and stable due to the packing of coiled fibrillar proteins in a rope like structure. The different types of intermediate filaments that can be found in the [[Cytoplasm|cytoplasm]] of different cells can be used in tumour characterisation techniques within the health and research industries. Different categories of cytoplasmic intermediate filaments are found in; the [[Epithelial cells|epithelia]] as keratins, the connective tissue as vimentin, and the nerve cells as neurofilaments. The main type of intermediate filaments found in the [[Nucleus|nucleus]] are called [[Nuclear lamins|nuclear lamins]] and are present in all nucleated cells, nuclear lamins lie just underneath the inner face of the [[Nuclear envelope|nuclear envelope]] and provide mechanical strength to the [[Nucleus|nucleus]] as well as providing attachment sites for the [[Chromosome|chromosomes]], but do break down during [[Mitosis|mitosis cell]] division <ref>Alberts,B., Johnson,A., Lewis, J., Raff, M., Roberts, K., and Watson, J. (2007). Molecular Biology of the Cell, 5th edition. Garland.</ref>. | ||
=== Reference === | === Reference === | ||
Revision as of 16:13, 25 November 2011
Intermediate filaments are a component of cytoskeleton. They are around 10 nm, and are present in both cytoplasm and nucleus. These help provide the cell with mechanical strength and are also strong and stable due to the packing of coiled fibrillar proteins in a rope like structure. The different types of intermediate filaments that can be found in the cytoplasm of different cells can be used in tumour characterisation techniques within the health and research industries. Different categories of cytoplasmic intermediate filaments are found in; the epithelia as keratins, the connective tissue as vimentin, and the nerve cells as neurofilaments. The main type of intermediate filaments found in the nucleus are called nuclear lamins and are present in all nucleated cells, nuclear lamins lie just underneath the inner face of the nuclear envelope and provide mechanical strength to the nucleus as well as providing attachment sites for the chromosomes, but do break down during mitosis cell division [1].
Reference
- ↑ Alberts,B., Johnson,A., Lewis, J., Raff, M., Roberts, K., and Watson, J. (2007). Molecular Biology of the Cell, 5th edition. Garland.