Dosage Compensation Mechanism: Difference between revisions
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Created page with "= Dosage Compensation = Mechanism by which X chromosome levels are re-established to levels seen in males. Such a mechanism only exists in females therefore. Dosage compensatio..." |
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= Dosage Compensation = | = Dosage Compensation = | ||
Mechanism by which X chromosome levels are re-established to levels seen in males. Such a mechanism only exists in females therefore. Dosage compensation requires RNA polymerase, Tsix transcript and Xist transcript as well as the X chromosomes of developing embryonic cells. Note that each transcript is transcribed on one chromosome each. Xist acts as to ensure inactivation of X chromosome whereas Tsix | Mechanism by which X chromosome levels are re-established to levels seen in males. Such a mechanism only exists in females therefore. Dosage compensation requires RNA polymerase, Tsix transcript and Xist transcript as well as the X chromosomes of developing embryonic cells. Note that each transcript is transcribed on one chromosome each. Xist acts as to ensure inactivation of X chromosome whereas Tsix ens<references />ures X chromosome remains active. Such activity is carried out from the [[X inactivation centre|X inactivation centre]]. | ||
Revision as of 17:42, 26 November 2011
Dosage Compensation
Mechanism by which X chromosome levels are re-established to levels seen in males. Such a mechanism only exists in females therefore. Dosage compensation requires RNA polymerase, Tsix transcript and Xist transcript as well as the X chromosomes of developing embryonic cells. Note that each transcript is transcribed on one chromosome each. Xist acts as to ensure inactivation of X chromosome whereas Tsix ensures X chromosome remains active. Such activity is carried out from the X inactivation centre.