Kinase: Difference between revisions
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A kinase is an [[Enzyme|enzyme]] that catalyses the addition of [[Phosphate|phosphate groups]] (phosphorylation) to specific substrates, forming a covalent bond with this substrate <ref>Molecular biology of the cell (5th edition), Alberts et al. Garland Science, 2008</ref>. There are currently 518 known protein kinase genes in the human genome.<ref name="null">Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S (2002) The protein kinase complement of the human genome. Science 298: 1912-1934</ref>Furthermore, kinases are commonly found in cell signalling pathways. | A kinase is an [[Enzyme|enzyme]] that catalyses the addition of [[Phosphate|phosphate groups]] (phosphorylation) to specific substrates, forming a [[covalent bond|covalent bond]] with this substrate <ref>Molecular biology of the cell (5th edition), Alberts et al. Garland Science, 2008</ref>. There are currently 518 known protein kinase genes in the human genome.<ref name="null">Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S (2002) The protein kinase complement of the human genome. Science 298: 1912-1934</ref> Furthermore, kinases are commonly found in [[cell signalling pathways|cell signalling pathways]]. | ||
=== References< | === References<br> === | ||
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Revision as of 20:57, 26 November 2011
A kinase is an enzyme that catalyses the addition of phosphate groups (phosphorylation) to specific substrates, forming a covalent bond with this substrate [1]. There are currently 518 known protein kinase genes in the human genome.[2] Furthermore, kinases are commonly found in cell signalling pathways.