Tropomyosin: Difference between revisions

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&nbsp;According to B. Alberts tropomyosin is an elongated protein, which stabilizes actin filaments by binding to seven adjacent actin subunits, thus preventing it from interacting with other proteins.<ref>B. Alberts, Molecular Biology of the Cell, Garland Science, 5th edition, 2008</ref>&nbsp;Tropomyosin, along with troponin play an important role in regulation of muscle contraction.<ref>R.D Keynes, D.J Aidley, Nerve and Muscle, 3rd edition, Cambridge University Press, 2001</ref>&nbsp;As tropomyosin binds to actin it follows its helical structure.<ref>B.Alberts, Molecular Biology of the Cell, 5th edition, Garland Science, 2008</ref> Fig.1


[[Image:Tropomyosin.gif|Accessory proteins troponin and tropomyosin on the actin filament]]<ref>San Diego State University (unknown), Skeletal Muscle Structure and Function, http://www-rohan.sdsu.edu/course/ens304/public_html/section1/Muscle.htm</ref>
This figure describes the relative position of accesory proteins and actin in a thin filament. Troponin complex is bound to actin and tropomyosin, which lies in the groove of the actin helix.
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Revision as of 12:46, 27 November 2011

 According to B. Alberts tropomyosin is an elongated protein, which stabilizes actin filaments by binding to seven adjacent actin subunits, thus preventing it from interacting with other proteins.[1] Tropomyosin, along with troponin play an important role in regulation of muscle contraction.[2] As tropomyosin binds to actin it follows its helical structure.[3] Fig.1

Accessory proteins troponin and tropomyosin on the actin filament[4]

This figure describes the relative position of accesory proteins and actin in a thin filament. Troponin complex is bound to actin and tropomyosin, which lies in the groove of the actin helix.

  1. B. Alberts, Molecular Biology of the Cell, Garland Science, 5th edition, 2008
  2. R.D Keynes, D.J Aidley, Nerve and Muscle, 3rd edition, Cambridge University Press, 2001
  3. B.Alberts, Molecular Biology of the Cell, 5th edition, Garland Science, 2008
  4. San Diego State University (unknown), Skeletal Muscle Structure and Function, http://www-rohan.sdsu.edu/course/ens304/public_html/section1/Muscle.htm