Tropomyosin: Difference between revisions
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According to B. Alberts tropomyosin is an elongated protein, which stabilizes actin filaments by binding to seven adjacent actin subunits, thus preventing it from interacting with other proteins.<ref>B. Alberts, Molecular Biology of the Cell, Garland Science, 5th edition, 2008</ref> Tropomyosin, along with troponin play an important role in regulation of muscle contraction.<ref>R.D Keynes, D.J Aidley, Nerve and Muscle, 3rd edition, Cambridge University Press, 2001</ref> As tropomyosin binds to actin it follows its helical structure.<ref>B.Alberts, Molecular Biology of the Cell, 5th edition, Garland Science, 2008</ref> Fig.1 | |||
[[Image:Tropomyosin.gif|Accessory proteins troponin and tropomyosin on the actin filament]]<ref>San Diego State University (unknown), Skeletal Muscle Structure and Function, http://www-rohan.sdsu.edu/course/ens304/public_html/section1/Muscle.htm</ref> | |||
This figure describes the relative position of accesory proteins and actin in a thin filament. Troponin complex is bound to actin and tropomyosin, which lies in the groove of the actin helix. | |||
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Revision as of 12:46, 27 November 2011
According to B. Alberts tropomyosin is an elongated protein, which stabilizes actin filaments by binding to seven adjacent actin subunits, thus preventing it from interacting with other proteins.[1] Tropomyosin, along with troponin play an important role in regulation of muscle contraction.[2] As tropomyosin binds to actin it follows its helical structure.[3] Fig.1
This figure describes the relative position of accesory proteins and actin in a thin filament. Troponin complex is bound to actin and tropomyosin, which lies in the groove of the actin helix.
- ↑ B. Alberts, Molecular Biology of the Cell, Garland Science, 5th edition, 2008
- ↑ R.D Keynes, D.J Aidley, Nerve and Muscle, 3rd edition, Cambridge University Press, 2001
- ↑ B.Alberts, Molecular Biology of the Cell, 5th edition, Garland Science, 2008
- ↑ San Diego State University (unknown), Skeletal Muscle Structure and Function, http://www-rohan.sdsu.edu/course/ens304/public_html/section1/Muscle.htm