Trisomy: Difference between revisions
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Trisomy is where there is an extra of a particular [[chromosome|chromosome]] due to [[Non_disjunction|nondisjunction]] during [[meiosis|meiosis]]. Trisomy often leads to miscarriage although there are a number of chromosomal abnormalities in which the foetus survives, mainly 13, 18, 21, X and Y. The chance of trisomy occuring increases with the age of the mother. | |||
Main non-lethal trisomies in humans: | |||
13-[ | *13-[[Patau Syndrome|Patau Syndrome]] | ||
*[[Patau Syndrome|Patau Syndrome]]18-[[Edward's Syndrome|Edward's Syndrome]] | |||
18- Edward's Syndrome | *21-[[Down's Syndrome|Down's Syndrome]]<ref>http://downsyndrome.about.com/od/whatcausesdownsyndrome/a/othtrisomies_ro.htm</ref> | ||
*[[X-Triplo|X-Triplo]] x or [[Trisomy X|Trisomy X]] | |||
21-[ | *Y- [[Klinefelter_syndrome|Klinefelter]] | ||
X- Triplo x or Trisomy X | |||
Y- [ | |||
Occassionally you can also get a tetrasomy in which there are four copies of a chromosome insteasd of two. | Occassionally you can also get a tetrasomy in which there are four copies of a chromosome insteasd of two. | ||
=== References === | |||
<references /> | <references /> | ||
Revision as of 21:07, 1 December 2011
Trisomy is where there is an extra of a particular chromosome due to nondisjunction during meiosis. Trisomy often leads to miscarriage although there are a number of chromosomal abnormalities in which the foetus survives, mainly 13, 18, 21, X and Y. The chance of trisomy occuring increases with the age of the mother.
Main non-lethal trisomies in humans:
- 13-Patau Syndrome
- Patau Syndrome18-Edward's Syndrome
- 21-Down's Syndrome[1]
- X-Triplo x or Trisomy X
- Y- Klinefelter
Occassionally you can also get a tetrasomy in which there are four copies of a chromosome insteasd of two.