G-proteins: Difference between revisions
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The [[G-proteins|G-proteins]] can be divided in to two families - the [[Heterotrimeric G-proteins|heterotrimeric G-proteins]] and the small or [[Mono-meric G-proteins|mono-meric G-proteins]]. | The [[G-proteins|G-proteins]] can be divided in to two families - the [[Heterotrimeric G-proteins|heterotrimeric G-proteins]] and the small or [[Mono-meric G-proteins|mono-meric G-proteins]]. | ||
G Proteins consist of 3 sub units ; an alpha, a beta and a gamma. There are 4 familys of alpha subunit : s,q,i and 12. In addition the beta and gamma subunits combine to form a dimer which also serves as a functional unit. | |||
Revision as of 11:37, 11 November 2010
Guanine nucleotide binding protein that binds GTP when activated, which it hydrolyses to GDP. The active form of the protein can interact with a number of down stream effectors such as adenylyl cyclase (producing cAMP from ATP), and phospholipase C (PLC).
The G-proteins can be divided in to two families - the heterotrimeric G-proteins and the small or mono-meric G-proteins.
G Proteins consist of 3 sub units ; an alpha, a beta and a gamma. There are 4 familys of alpha subunit : s,q,i and 12. In addition the beta and gamma subunits combine to form a dimer which also serves as a functional unit.