G-proteins: Difference between revisions

Revision as of 12:53, 11 November 2010

Guanine nucleotide binding protein that binds GTP when activated, which it hydrolyses to GDP. The active form of the protein can interact with a number of down stream effectors such as adenylyl cyclase (producing cAMP from ATP), and phospholipase C (PLC).

The G-proteins can be divided in to two families - the heterotrimeric G-proteins and the small or mono-meric G-proteins.

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 [[Guanine nucleotide|Guanine nucleotide]] binding [[Protein|protein]] that binds [[GTP|GTP]] when activated, which it hydrolyses to [[GDP|GDP]]. &nbsp;The active form of the [[Protein|protein]]&nbsp;can interact with a number of down stream effectors such as [[Adenylyl cyclase|adenylyl cyclase]]&nbsp;(producing [[CAMP|cAMP]] from [[ATP|ATP]]), and&nbsp;[[Phospholipase C|phospholipase C]] ([[PLC|PLC]]).
-The [[G-proteins|G-proteins]] can be divided in to two families - the [[Heterotrimeric G-proteins|heterotrimeric&nbsp;G-proteins]] and the small or [[Mono-meric G-proteins|mono-meric G-proteins]].
+The [[G-proteins|G-proteins]] can be divided in to two families - the [[Heterotrimeric G-proteins|heterotrimeric&nbsp;G-proteins]] and the small or [[Mono-meric G-proteins|mono-meric G-proteins]].<br>
-G Proteins consist of 3 sub units ; an alpha, a beta and a gamma. There are 4 familys of alpha subunit : s,q,i and 12. In addition the beta and gamma subunits combine to form a dimer&nbsp;which also serves as a functional unit.