Enzyme-substrate complex: Difference between revisions

From The School of Biomedical Sciences Wiki
Jump to navigation Jump to search
Created page with "Enzyme-Substrate (ES) complexes are formed during enzyme catalysed chemical reactions. Every enzyme is equipt with a 'cleft' in its structure which is complementary to a pa..."
 
No edit summary
Line 1: Line 1:
Enzyme-Substrate (ES) complexes are formed during enzyme catalysed chemical reactions.
Enzyme-Substrate (ES) complexes are formed during enzyme catalysed chemical reactions.  


Every enzyme is equipt with a 'cleft' in its structure which is complementary to a particular substrate. This is known as the active site. As well as shape, specificity of the active site is developed further via the amino acid R-Groups&nbsp;within&nbsp;the&nbsp;site. These groups will interact specifically with the substrate molecule(s). <ref>www.biog1105-1106.org/demos/105/unit3/media/enzymes.pdf</ref>The ES&nbsp;complex is the state in which the active site of the enzyme is non covalently bound to the substrate molecule(s).&nbsp;This is&nbsp;where the chemical reaction occurs.  
Every enzyme is equipt with a 'cleft' in its structure which is complementary to a particular substrate. This is known as the active site. As well as shape, specificity of the active site is developed further via the amino acid R-Groups&nbsp;within&nbsp;the&nbsp;site. These groups will interact specifically with the substrate molecule(s). <references /><ref name="www.biog1105-1106.org/demos/105/unit3/media/enzymes.pdf">www.biog1105-1106.org/demos/105/unit3/media/enzymes.pdf</ref>The ES&nbsp;complex is the state in which the active site of the enzyme is non covalently bound to the substrate molecule(s).&nbsp;This is&nbsp;where the chemical reaction occurs.  


<br>


ENZYME&nbsp;+&nbsp;SUBSTRATE&nbsp;-&gt; ENZYME SUBSTRATE COMPLEX -&gt; ENZYME&nbsp;+ PRODUCT&nbsp;


ENZYME&nbsp;+&nbsp;SUBSTRATE&nbsp;-&gt; ENZYME SUBSTRATE COMPLEX -&gt; ENZYME&nbsp;+ PRODUCT&nbsp;
<br>
 
 


The following is a useful video demonstrating&nbsp;the formation of an Enzyme Substrate Complex:&nbsp;[http://www.youtube.com/watch?v=Tn7HJphCBgc www.youtube.com/watch]
The following is a useful video demonstrating&nbsp;the formation of an Enzyme Substrate Complex:&nbsp;[http://www.youtube.com/watch?v=Tn7HJphCBgc www.youtube.com/watch]

Revision as of 14:43, 25 October 2012

Enzyme-Substrate (ES) complexes are formed during enzyme catalysed chemical reactions.

Every enzyme is equipt with a 'cleft' in its structure which is complementary to a particular substrate. This is known as the active site. As well as shape, specificity of the active site is developed further via the amino acid R-Groups within the site. These groups will interact specifically with the substrate molecule(s). [1]The ES complex is the state in which the active site of the enzyme is non covalently bound to the substrate molecule(s). This is where the chemical reaction occurs.


ENZYME + SUBSTRATE -> ENZYME SUBSTRATE COMPLEX -> ENZYME + PRODUCT 


The following is a useful video demonstrating the formation of an Enzyme Substrate Complex: www.youtube.com/watch

  1. www.biog1105-1106.org/demos/105/unit3/media/enzymes.pdf