Integral and peripheral membrane proteins: Difference between revisions

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Peripheral membrane proeins bind integral proeins by noncovalent interactions
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These proteins are connected to the plasma membrane through intermediate molecules (even integral proteins) or proteins attached to only one side of the membrane; do not pass through the membrane <ref>Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell. 4th edition. New York: Garland Science; 2002</ref>.<br>  
These proteins are connected to the plasma membrane through intermediate molecules (even integral proteins) or proteins attached to only one side of the membrane; do not pass through the membrane <ref>Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell. 4th edition. New York: Garland Science; 2002</ref>.<br>  


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Revision as of 18:35, 17 October 2013

Integral Membrane Proteins

These are proteins directly linked to the plasma membrane of cells; they do not have intermediate molecules between them and the plasma membranes. They are also considered as proteins that fully pass through the membrane (carrier proteins and channel proteins).

Peripheral Membrane Proteins

These proteins are connected to the plasma membrane through intermediate molecules (even integral proteins) or proteins attached to only one side of the membrane; do not pass through the membrane [1].

Reference

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  1. Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell. 4th edition. New York: Garland Science; 2002