Integral and peripheral membrane proteins: Difference between revisions

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Integral membranes can be extracted from the membrane using a detergent. They can be classed as either cytosolic, cell surface or transmembrane integral proteins.
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=== Peripheral Membrane Proteins  ===
=== Peripheral Membrane Proteins  ===


These proteins are connected to the plasma membrane through intermediate [[Molecules|molecules]] (even integral proteins) by noncovalent interactions or proteins attached to only one side of the membrane; do not pass through the membrane <ref>Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell. 4th edition. New York: Garland Science; 2002</ref>.<br>  
These proteins are connected to the plasma membrane through intermediate [[Molecules|molecules]] (even integral proteins) by noncovalent interactions. They can be removed fro the membrane fairly easily by simply increasing the salt concentration of the buffer solution which the cells are suspended in.<br>


=== Reference  ===
=== Reference  ===


<references />
<references />

Revision as of 16:33, 20 October 2013

Integral Membrane Proteins

These are <a href="Proteins">proteins</a> directly linked to the <a href="Plasma membrane">plasma membrane</a> of <a href="Cells">cells</a>; they do not have intermediate <a href="Molecules">molecules</a> between them and the <a href="Plasma membranes">plasma membranes</a>. They are also considered as proteins that fully pass through the membrane (<a href="Carrier protein">carrier proteins</a> and <a href="Channel protein">channel proteins</a>).

Peripheral Membrane Proteins

These proteins are connected to the plasma membrane through intermediate molecules (even integral proteins) by noncovalent interactions. They can be removed fro the membrane fairly easily by simply increasing the salt concentration of the buffer solution which the cells are suspended in.

Reference