Missense mutation: Difference between revisions
Jump to navigation
Jump to search
Created page with " A missense mutation occurs when there is a base subsitution for example, A being changed to C, which will then causes an [[Amino_acid|ami..." |
No edit summary |
||
| Line 1: | Line 1: | ||
A missense [[Mutations|mutation]] occurs when there is a [[Base Subsitution|base subsitution]] for example, A being changed to C, which will then causes an [[Amino acid|amino acid]] alteration. If this mutation where to happen in the codon CAT, it would change to CCT and so the amino acid produced would be altered from His to Pro. Due to this alteration in amino acid sequence there will be a knock on affect on the final[[Protein structure|protein structure]] and therefore its function<ref>Daniel L. Hartl, Maryellen Ruvolo,(2012),Genetics Analysis of Genes and Genomes, 8th edition, United States of America: Jones and Bartlett Learning LLC, an Ascend Learning Company. Chapter 14, Page 524,525.</ref>. | |||
=== Reference === | === Reference === | ||
<references /> | |||
Revision as of 00:18, 25 October 2013
A missense mutation occurs when there is a base subsitution for example, A being changed to C, which will then causes an amino acid alteration. If this mutation where to happen in the codon CAT, it would change to CCT and so the amino acid produced would be altered from His to Pro. Due to this alteration in amino acid sequence there will be a knock on affect on the finalprotein structure and therefore its function[1].
Reference
- ↑ Daniel L. Hartl, Maryellen Ruvolo,(2012),Genetics Analysis of Genes and Genomes, 8th edition, United States of America: Jones and Bartlett Learning LLC, an Ascend Learning Company. Chapter 14, Page 524,525.