Fatty acid metabolism: Difference between revisions

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It is adenylyl not adenylate. Cleaned up text and added in links.
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<p>Fatty acids are a source of metabolic energy to be used by muscle cells during exercise. Ingested fats are digested and used as an immediate source of energy by respiring cells or stored in adipocytes (fat cells) as fat droplets.<span class="fck_mw_ref">http://www.wiley.com/college/boyer/0470003790/animations/fatty_acid_metabolism/fatty_acid_metabolism.htm</span> <br />During a prolonged period of exercise, energy stored as fat droplets in adipocytes is mobilised as glycogen stores are used up. Epinephrine or glucagon bind to receptors on adipocyte cell membranes and initiate a secondary messenger response. Adenylate cyclase is activated to convert ATP to cAMP, which in turn binds to Protein Kinase and activates it. Activated Protein Kinase activates Triglycerol Lipases which break down triglycerols into three fatty acid molecules.<span class="fck_mw_ref">http://www.wiley.com/college/boyer/0470003790/animations/fatty_acid_metabolism/fatty_acid_metabolism.htm</span> <br />Fatty acid molecules are taken up by the serum albumin in the bloodstream. The fatty acid molecules are transported to respiring muscle cells to undergo β-oxidation. This reaction produces ATP and carbon dioxide.<span class="fck_mw_ref">http://www.wiley.com/college/boyer/0470003790/animations/fatty_acid_metabolism/fatty_acid_metabolism.htm</span>
Fatty acids are a source of metabolic energy to be used by muscle cells during exercise. Ingested fats are digested and used as an immediate source of energy by respiring cells or stored in [[adipocytes|adipocytes]] (fat cells) as fat droplets<ref>http://www.wiley.com/college/boyer/0470003790/animations/fatty_acid_metabolism/fatty_acid_metabolism.htm</ref>.
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During a prolonged period of exercise, energy stored as fat droplets in adipocytes is mobilised as [[glycogen|glycogen]] stores are used up. [[Epinephrine|Epinephrine]] or [[glucagon |glucagon]] bind to receptors on adipocyte cell membranes and initiate a [[secondary messenger|secondary messenger]] response. [[Adenylyl cyclase|Adenylyl cyclase]] is activated to convert [[ATP|ATP]] to [[cAMP|cAMP]], which in turn binds to [[Protein Kinase A|Protein Kinase A]] and activates it. Activated Protein Kinase activates [[Triglycerol Lipase|Triglycerol Lipases]] which break down [[triglycerols|triglycerols]] into three fatty acid molecules<ref>http://www.wiley.com/college/boyer/0470003790/animations/fatty_acid_metabolism/fatty_acid_metabolism.htm</ref>.
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<h1> References </h1>
Fatty acid molecules are taken up by the serum [[albumin|albumin]] in the bloodstream. The fatty acid molecules are transported to respiring muscle cells to undergo [[beta-oxidation|β-oxidation]]. This reaction produces ATP and [[carbon dioxide|carbon dioxide]] <ref>http://www.wiley.com/college/boyer/0470003790/animations/fatty_acid_metabolism/fatty_acid_metabolism.htm</ref>.
<h1> &lt;span class="fck_mw_references" _fck_mw_customtag="true" _fck_mw_tagname="references" /&gt;&#160;<br />&#160;&#160; </h1>
 
=== References ===
 
<references />

Revision as of 01:46, 20 November 2013

Fatty acids are a source of metabolic energy to be used by muscle cells during exercise. Ingested fats are digested and used as an immediate source of energy by respiring cells or stored in adipocytes (fat cells) as fat droplets[1].

During a prolonged period of exercise, energy stored as fat droplets in adipocytes is mobilised as glycogen stores are used up. Epinephrine or glucagon bind to receptors on adipocyte cell membranes and initiate a secondary messenger response. Adenylyl cyclase is activated to convert ATP to cAMP, which in turn binds to Protein Kinase A and activates it. Activated Protein Kinase activates Triglycerol Lipases which break down triglycerols into three fatty acid molecules[2].

Fatty acid molecules are taken up by the serum albumin in the bloodstream. The fatty acid molecules are transported to respiring muscle cells to undergo β-oxidation. This reaction produces ATP and carbon dioxide [3].

References

  1. ↑ http://www.wiley.com/college/boyer/0470003790/animations/fatty_acid_metabolism/fatty_acid_metabolism.htm
  2. ↑ http://www.wiley.com/college/boyer/0470003790/animations/fatty_acid_metabolism/fatty_acid_metabolism.htm
  3. ↑ http://www.wiley.com/college/boyer/0470003790/animations/fatty_acid_metabolism/fatty_acid_metabolism.htm
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