Abc transporter protein: Difference between revisions
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ABC transporters are a family of transport proteins that primarily transport small molecules. ABC transporters are composed of two catalytic ATPase domains, when ATP binds the two domains dimerize, and when ATP is hydrolyzed they dissociate. The conformational change in the ABC transporter results in a change in the membrane itself, revealing a substrate binding site. This is thought to be how ABC transporters move small molecules across membranes.<ref>Alberts, B et al., 2007. Molecular Biology of the Cell, 5th edition. Garland Science, pg. 663</ref> | ABC transporters are a family of transport [[proteins|proteins]] that primarily transport small [[molecules|molecules]]. ABC transporters are composed of two catalytic [[ATPase domain|ATPase domains]], when [[ATP|ATP]] binds the two domains dimerize, and when ATP is hydrolyzed they dissociate. The conformational change in the ABC transporter results in a change in the membrane itself, revealing a substrate binding site. This is thought to be how ABC transporters move small molecules across membranes.<ref>Alberts, B et al., 2007. Molecular Biology of the Cell, 5th edition. Garland Science, pg. 663</ref><br> | ||
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Revision as of 03:05, 27 November 2013
ABC transporters are a family of transport proteins that primarily transport small molecules. ABC transporters are composed of two catalytic ATPase domains, when ATP binds the two domains dimerize, and when ATP is hydrolyzed they dissociate. The conformational change in the ABC transporter results in a change in the membrane itself, revealing a substrate binding site. This is thought to be how ABC transporters move small molecules across membranes.[1]
References
- ↑ Alberts, B et al., 2007. Molecular Biology of the Cell, 5th edition. Garland Science, pg. 663