GLUT1

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GLUT's are family of proteins which aim to transport glucose using its downhill gradient across membranes. There are many different GLUT's, however, each has a significantly different role in the transport of molecules. [1] FOr example, GLUT1 is a type of glucose transporter found in the cell membrane of erythrocyte and brain cells and is encoded by the gene SLC2A [2]. The GLUT family of glucose transporters are an example of uniporters, meaning that the carrier protein transports one substrate. Whereas, GLUT<span style="line-height: 1.5em;" /> 5, for example, is used more often to transport fructose across membranes. [3]

References

  1. Berg.J.M, Stryer.L, Tymoczko J.L, Biochemistry, seventh edition, WH Freeman, 2012 page 493
  2. Leszek Szablewski, 2011, Glucose Homeostasis and Insulin resistance (e-book), Bentham Science Publisher, Available through:
  3. Berg.J.M, Stryer.L, Tymoczko J.L, Biochemistry, seventh edition, WH Freeman, 2012 page 493