Adenylyl cyclase
Adenyl Cyclase is the enzyme that converts ATP into Cyclic AMP (cAMP) which is a secondary messenger.It has a major role in activating of enzymes and hormones for example: epinephrine, vasopressin and glucagon. It is an integral membrane protein that has the structure of two bundles of six transmembrane segments and two catalytic domains that extend as loops into the cytoplasm. The enzyme can exist in at least 9 isoforms that are regulated in different ways by different G protein coupled receptors [1].
References
Henrik Heldin,Carl,Signal trasduction,
- ↑ Bowen R November 29th 2003 http://www.vivo.colostate.edu/hbooks/molecules/cyclase.html