DNA polymerase I
DNA polymerase I is an enzyme that is involved in DNA replication in E'.coli
1) 5’→3’ exonuclease activity to remove RNA primers ahead of the polymerase site[1].
2) 3’→5’ exonuclease activity for proof-reading and accuracy.
References
- ↑ Berg J, Tymoczko J, Stryer L (2007) Biochemistry, 6th edition, New York: W.H. Freeman, p. 801