X inactivation centre

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X inactivation centre

X inactivation centre or 'XIC' is a region of the X chromosome which includes Xist and Tsix transcripts transcribing either side of the chromosome. It is the location to which dosage compensation and therefore chromosomal inactivation occurs within females. ^[1]

↑ Lodish et,al. (Molecular Cell Biology) 6th edition, pg959

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