Activator
Activator domains are modular proteins that stimulate transcription via communicating with the transcription machinery "pre-initation complex" (PIC).[1]
Activators
They work synergistically as it promotes binding of an additional activator. They bound to an enhancer to facilitate either the recruitment of RNA polymerase II to the promoter region or its elongation .[2]
References
- ↑ Lodish, H. et al.,2007.Molecular Cell Biology.Sixth Edition.New york:W.H.Freeman & Co Ltd.
- ↑ http://www.ncbi.nlm.nih.gov/pubmed/22180087
transcriptional activators and mechanisms (http://www.ncbi.nlm.nih.gov/pubmed/22180087)