Turner syndrome

From The School of Biomedical Sciences Wiki
Revision as of 15:22, 29 November 2012 by 120424656 (talk | contribs)
Jump to navigation Jump to search

Turner Syndrome is a monosomic condition in which only one X chromosome is present (XO). A person with this syndrome will have no barr bodies as they only have 1 X chromosome. Instead of having a set of 44 autosomes + 1 pair of sex chromosomes (either XX or XY), the person has only 44 autosomes + 1 X chromosomes. Turner syndrome ocurrs as a result of nondisjunction, which is when chromosomes do not separate successfully during meiosis. It happens in about 1 in 5000 female births. The affected females are of a characteristic phenotype e.g sterile, have a short height, low hairline, small finger nails, and poor breast development with the nipples spread a distance apart [1].

References

  1. Anthony JF Griffiths et al., 1990, Modern Genetic Analysis, New York : W.H.Freeman, Chapter 8