GLUT3

GLUT-3 is a glucose transporter within cell membranes. It is one of 14 Na+ independent facilitated diffusion transporters, termed GLUT-1 to GLUT-14. As it is a facilitated diffusion transporter, it relies on a concentration gradient for transport of glucose.

GLUT-3 binds to glucose in the extracellular space (e.g. blood) which induces a conformational change. This conformational change transports the glucose across the cell membrane.

GLUT-3 is primarily involved in glucose transport for neurones and, unlike some transporters, principally tranports glucose to within the cells, rather than bidirectionally.