Proteomics

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Proteomics is the study of  total proteins which is expressed by a cell, tissue or an organism[1]. Meanwhile, genomics is the study of structure and roles of the whole gene products[2]. There are a few crucial differences between proteomics and genomics. In biological fluids such as plasma, serum, urine, cells and tissues, a marker called as "Proteomic biomarkers" is used to mark the molecules[3]. Besides, if there is a stimuli from the environment or surroundings, the proteome(proteins) will react with the stimuli and keep changing in constant[4]. Furthermore, in every cells or tissues, the proteome is different from each other due to different genes carried[5]. Existence of  post-translational modifications and protein conformation will cause in addition of the complexity[6]. Thus, only Polymerase Chain Reaction(PCR)  produces total of proteome faster and ease to amplify them to an assay[7]. These reasons proves that the proteome potrays the transcriptome more than the genome itself[8].

  1. Trent, R.J. (2012) Molecular Medicine Genomics to personalized healthcare : Proteomics. 4 , 137. USA : Elsevier
  2. Primrose S.B. , Twyman R.M. (2003). Principle of Genome Analysis and Genomics. 3, 9. Hong Kong: Graphicraft Limited.
  3. Primrose S.B. , Twyman R.M. (2003). Principle of Genome Analysis and Genomics. 3, 9. Hong Kong: Graphicraft Limited.
  4. Primrose S.B. , Twyman R.M. (2003). Principle of Genome Analysis and Genomics. 3, 9. Hong Kong: Graphicraft Limited.
  5. Primrose S.B. , Twyman R.M. (2003). Principle of Genome Analysis and Genomics. 3, 9. Hong Kong: Graphicraft Limited.
  6. Primrose S.B. , Twyman R.M. (2003). Principle of Genome Analysis and Genomics. 3, 9. Hong Kong: Graphicraft Limited.
  7. Primrose S.B. , Twyman R.M. (2003). Principle of Genome Analysis and Genomics. 3, 9. Hong Kong: Graphicraft Limited.
  8. Primrose S.B. , Twyman R.M. (2003). Principle of Genome Analysis and Genomics. 3, 9. Hong Kong: Graphicraft Limited.