Retinitis pigmentosa

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Retinitis pigmentosa is a disease that involves the break down of retina cells in the eye caused by a mutation in the RHO gene located on chromosome 3q22[1]. It can lead to loss of peripheral vision and weakened night vision[2].

Treatment methods include: the suppression and replacement of the gene or using zinc finger transcription factors[3].

  1. http://omim.org/entry/613731 cited 19/10/17
  2. https://nei.nih.gov/health/pigmentosa/pigmentosa_facts cited 19/10/17
  3. Farrar G.J., Millington-Ward S., Palfi A., Chadderton N., Kenna P.F. (2015) Gene Therapy for Dominantly Inherited Retinal Degeneration. In: Rakoczy E. (eds) Gene- and Cell-Based Treatment Strategies for the Eye. Essentials in Ophthalmology. Springer, Berlin, Heidelberg