Ischemia

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Ischemia occurs when plaque hardens and forms a clot in the arteries. As a result the blood flow through the arteries is reduced. The plaque itself is made up of metabolic waste products formed through an ischemic cascade.[1] In the case of cardiac ischemia, the blood flow to the heart is decreased thus leading to myocardial infarction. [2]

  1. 'Pathophysiologic cascades in ischemic stroke' Int J Stroke. 2012 Jul; 7(5): 378–385
  2. http://www.webmd.com