Retrotransposon

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Retrotransposon are a class of transposons which operate by DNA being transcribed into RNA then back to DNA again, via the action of reverse trnascriptase[1]. They are also known as 'jumping genes' as DNA is moved to a different position on the chromosome each time retrotransposition occurs[2]


There are 2 types of retrotransposons[3]

1. Long Terminal Receptors (LTRs

These have structures similar to retroviruses

2. Non-Long Terminal Receptors (non LTRs

These are further divided into Long Interspersed Nuclear Elements (LINEs) and Short Interspersed Nuclear Elements (SINEs

  1. Lander E, Linton L, Birren B, Nusbaum C, Zody M, Baldwin J et al. Initial sequencing and analysis of the human genome. Nature [Internet]. 2001
  2. Lander E, Linton L, Birren B, Nusbaum C, Zody M, Baldwin J et al. Initial sequencing and analysis of the human genome. Nature [Internet]. 2001
  3. The three Types of Retrotransposons [Internet]. Actforlibraries.org. 2018