Metastasis

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Metastasis is the multistep process by which cancer cells within a malignant tumour escape and form secondary tumours (metastases) at a distant organ in the body. Successful invasion of blood or lymphatic vessels by malignant cells precedes the formation of a micrometases at the new site before complete colonisation to the secondary tumour. Resistance to apoptosis is an attribute thought to enable such cells to survive in a foreign environment.

References

[1]

  1. Alberts et al. Molecular Biology of the Cell (2008) 5th Edition. New York: Garland Science.