Isoleucine

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Isoleucine is a hydrophobic neutral amino acid, the reason why its hydrophilic is because it has a aliphatic side chain. Isoleucine has an additional chiral centre at carbon 3 [1].

References

  1. Berg J., Tymoczko J and Stryer L. (2007) Biochemistry, 6th edition, New York: WH Freeman