PI3Ka domain

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PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation.

The information achieved is from the wibesite below:

http://smart.embl-heidelberg.de/smart/do_annotation.pl?DOMAIN=PI3Ka&START=858&END=1044&E_VALUE=7.11e-93&TYPE=SMART&BLAST=NVSSRGGKKFLPVLKEILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSK

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