MAP Kinase Kinase Kinase

MAP Kinase Kinase Kinase ( also called MAP3K) is a type of protein kinase that phosphorylates other proteins, which include protein kinases such as Map Kinase Kinase (MEK). As this protein kinase phosphorylates a MEK, it is known as MEKK. This protein kinase aids in cell proliferation, cell death, hormonal responses and cell differentiation by acting as a messengers in cascade of kinases pathways in order to deliver a message to the cell.

One of the functions of MAP3K is that it phosphorylates the Serine or the Threonine residues of MEK. This can be shown through the RAS signalling pathways