Cyclic AMP

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Cyclic AMP (cAMP) is a second messenger used in cell signalling. It is synthesised from ATP by the enzyme adenylyl cyclase. [1] 

1. Alberts et al (2008). "Molecular Biology of the Cell" (5th edition); page 906.


Production of cyclic AMP results in the activation of Protein kinase A, which triggers cellular responses by activating enzymes, stimulating cellular secretion or opening ion channels.

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