B cells

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 B cells or B lymphocytes develop from hematopoietic stem cells in the bone marrow and are involved in the humoral response. The receptor of the B cell binds antigen and delivers this inside the cell in a vesicle where the antigen undergoes processing and is then presented on the cell surface as a complex with an MHC class 2 molecule. CD4+ T cells then respond to this antigen presentation by releasing cytokines leading to B cell proliferation and differentiation. B cells differentiate into plasma memory cells and antibody secreting cells. 


Reference:

Murphy, K. (2012) Janeway's Immunobiology. 8th Edition. New York: Garland Sciences. Chapter 8.1 and Chapter 10 introduction. 

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