Guanosine diphosphate

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Guanosine diphosphate, also known as GDP when shortened to an abbreviation, Guanosine 5'-diphosphate and Guanosine pyrophosphate[1]. It is a nucleoside diphosphate and is an ester of pyrophosphoric acid combined with a nucleoside guanosine molecule. It is made up of a pyrophosphate group, a pentose sugar ribose and the nucleobase guanine[2]


GDP can be converted into GTP with the help of pyruvate kinase and phosphoenolpyruvate. GDP is also the product of GTP dephosphorylation by GTPases, e.g. the G-proteins that are involved in signal transduction[3]


References