ANTI-INFLAMMATORY DRUGS

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There are two groups of anti-inflammatory drugs:

  1. Non-steroidal anti-inflammatory drugs
  2. Steroidal anti-inflammatory drugs.

Non-steroidal anti-inflammatory drugs, also referred to as NSAID's often act on COX-2 enzymes which are mainly in the human central nervous system in order to treat pain; this is the mechanism of action for paracetamol[1]. NSAID's also inhibit the activity of COX-1 (cyclooxygenase-1) enzymes.

References

  1. Hinz,B. Cheremina, O. Brune, K. (2008) 'Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trials', The Journal of the Federation of American Societies for Experimental Biology, vol. 22, no. 2, February, pp. 383-390. doi:10.1096/fj.07-8506com.