Guanine nucleotide exchange factor

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Guanine nucleotide exchange factors (GEF) activate small GTPases such as Ras by mediating the dissociation of GDP allowing GTP to bind [1].

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  1. ↑ Alberts R, Johnson A, Lewis J, Morgan D, Raff M, Roberts K, Walter P. (2015) Molecular biology of the cell. 6th ed. New York: Garland Science. (p. 157)
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