Ca2+ ions

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 Ca2+ ions play a important role in muscle contraction by creating interactions between the proteins myosin and actin. The Ca2+ ions bind to the C component of the actin filament, which exposes the binding site for the myosin head to bind to in order to stimulate a muscle contraction. 


References: 

A G Szent-Györgyi. Calcium regulation of muscle contraction. July 1975 [cited: 26/11/17]: Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1334730/