P13Kc domain

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Phosphoinositide 3-kinases (PI3k) are involved in Ras pathway, vesicle trafficking and secretion, apoptosis and other cellular processes. P13Kc domain is the catalytic domain and consists of a small N terminal and a large C terminal[1].

References

  1. ↑ Smart. Available at: http://smart.embl-heidelberg.de/smart/do_annotation.pl?DOMAIN=PI3Kc&START=1134&END=1400&E_VALUE=1.63211241435305e-133&TYPE=SMART&BLAST=GVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKD. [Accessed 23 October 2018].




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