Transition mutation

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A Transition mutation occurs when a purine base (adenine/guanine) is substituted for a fellow purine base or a pyrimidine base (cytosine/thymine) is substituted for a fellow pyrimidine base. It is the opposite of a transversion mutation which occurs when a pyrimidine is exchanged for a purine base, or vice-versa[1].

References

  1. Hartl D, Ruvolo M (2011), Genetics 8th edition, Massachusettes, Jones & Bartlett Learning