GDP

Guanosine diphosphate (GDP)

Molecular formula: C₁₀H₁₅N₅O₁₁P₂ 

Guanosine diphosphate is a purine nucleoside diphosphate, and is a product of the dephosphorylation of guanosine triphosphate (GTP) by GTPases. The conversion of GTP to GDP (and vice versa) has a physiological involvment in G-Protein signal transduction, whereby the G-Protein exchanges it's bound GDP for GTP, leaving it in an active state. For the conversion GDP to GTP, the enzymes pyruvate kinase and phosphoenolpyruvate are necessary.