GTPase

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Overview

GTPases are a group of enzymes which hydrolyse GTP to GDP (a phosphate group is removed). They play an important roll in cell signalling pathways for example, GTP/GDP bound G proteins have intrinsic GTPase activity to slowly reset themselves to their resting state state once it has fullfilled its function[1]. They are also involved in the synthesis of proteins at the Ribosome.[2]


References
  1. Berg J, Tymoczko J and Stryer L, 2007. Biochemistry, 6th Edition, New York: W.H.Freeman & Co Ltd. (page 387)
  2. Berg J, Tymoczko J and Stryer L, 2007. Biochemistry, 6th Edition, New York: W.H.Freeman & Co Ltd. (page 881)