IgG

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Immunoglobulin G ( IgG ) is an antibody, which is abundant in the blood, lumph and extracellular fluid.[1]

It plays various roles in the immune response, but primarily , it aids the phagocytosis of pathogens and alleviated their destruction.[2] IgG acts by coating the microorganism , a process known as 'opsonisation' and then binds to phagocytes through its constant regions. Being coated by the IgG, the pathogen is captured by the neutrophils and the macrophages and undergoes destruction by the latter.[3]


References:

  1. Parham,P. (2009) The Imuune System, 3rd edition, New York, Garland Science
  2. Parham, P. (2009)The Immune System, 3rd edition, New York, Garland Science
  3. Parham, P. (2009)The Immune System, 3rd edition, New York, Garland Science