Escherichia coli
Escherichia coli is a gram negative facultative anaerobic rods commonly found in the intestinal tracts of animals. This type of bacteria is capable of growing and metabolizing glucose both in aerobbic conditions and in anaerobic conditions because it is capable of surviving in external aerobic environments as well as internal anaerobic environment such as the gastrointestinal tract of warm blooded animals.[1] E. coli thrives in the intestines in the intestines of animals both in health and disease. E. coli aids in the process of digestion, helps in the absorption of many important nutrients and protects the gastrointestinal tract from various harmful bacteria.[2] Most strains of E. coli are harmless, while other strains may produce toxins that can cause various types of diseases in humans.[3] Many strains of E. coli are harmless, however some can be pathogenic like for example E. coli 0157 which can be a seriuos cause of gastroenteritis [4].
E. coli is often used as a model organinsm in lab experiments due to its fast reproduction time, how easily it is manipulated and its already sequenced genome. The E. coli strain K-12 is the strain most commonly used in the laboratory. It has 4.6 million nucleotide pairs in its genome that code for approxamately 4300 different proteins [5].
References
- ↑ Todar,K. Pathogenic E. coli [online] in: http://www.textbookofbacteriology.net/e.coli.html
- ↑ Hu, A. Looks can be deceiving: the case of Escherichia coli [online] in: http://www.jyi.org/volumes/volume6/issue5/features/hu.html
- ↑ Harrison, K. Types of Diseases caused by E. coli [online] in: http://www.livestrong.com/article/132628-types-diseases-caused-e-coli/
- ↑ http://www.ncbi.nlm.nih.gov/pubmed/20971366?tool=MedlinePlus
- ↑ Alberts. B, Johnson A, Lewis. J, Raff. M, Roberts. K, Walter. P, (2008), Molecular Biology Of The Cell, fifth edition, Garland Science, Taylor and Francis group, New York, p25