Kinase

From The School of Biomedical Sciences Wiki
Revision as of 20:57, 26 November 2011 by Nnjm2 (talk | contribs)
Jump to navigation Jump to search

A kinase is an enzyme that catalyses the addition of phosphate groups (phosphorylation) to specific substrates, forming a covalent bond with this substrate [1]. There are currently 518 known protein kinase genes in the human genome.[2] Furthermore, kinases are commonly found in cell signalling pathways.

References

  1. Molecular biology of the cell (5th edition), Alberts et al. Garland Science, 2008
  2. Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S (2002) The protein kinase complement of the human genome. Science 298: 1912-1934