Induced fit mechanism
The substrate approaches the enzyme's active site and binds to it. The binding induces the active site to change its shape to fit complementary to the substrate [1]. When the catalytic reaction terminates, the products leave the active site and the enzyme returns to its original configuration.
Reference
- ↑ Berg,J.M.,Tymoczko,J.L.,Stryer,L.(2007)Biochemistry, sixth ed, New York:W.H. Freeman and Company,pp.215